Craig Mayer, Nick WIlliams, Vojtech Huser
Lister Hill National Center for Biomedical Communications, National Library of Medicine, NIH, Bethesda, MD

See the full regCTG repository at https://github.com/lhncbc/CRI/tree/master/regCTG

To return to the list of conditions and view other reports go to https://lhncbc.github.io/CRI/regCTG/regCTG-condition_report_links.html


Study Counts

Type Study_count
Total_Studies 162
interventional 118
Observational 40
Registry 4

Studies over Time by Start Date

```

Interventional Trials

Intervention Type

intervention_type Study_Count
Drug|placebo 34
Drug 29
Behavioral 10
Device 10
Other 8
Procedure 6
Biological 4
Behavioral|Other 3
Device|Other 3
Dietary Supplement 2
Dietary Supplement|placebo 2
Drug|Procedure 2
Behavioral|Dietary Supplement|placebo 1
Device|Drug 1
Device|Procedure 1
Diagnostic Test 1
Other|Procedure 1

Count of Studies by Intervention (normalized and mapped)

Interventions over Time

Yearly studies for each intervention by start date

Studies by Country

Country Study_Count
United States 39
NA 15
Brazil 10
Finland 4
Israel 4
Spain 3
United Kingdom 3
Canada 2
Sweden 2
Taiwan 2
Turkey 2
Argentina|Australia|Austria|Brazil|Bulgaria|Canada|China|France|Germany|Hungary|Israel|Mexico|Singapore|Slovakia|Switzerland|Thailand|Italy 1
Argentina|Belgium|Brazil|Canada|Denmark|France|Germany|Greece|Iceland|Italy|Norway|Romania|Singapore|South Africa|Spain|Sweden|Switzerland 1
Argentina|Brazil|Chile|Colombia|Costa Rica|Ecuador|Mexico|Peru|Uruguay|Venezuela 1
Belarus|Belgium|Czechia|Denmark|Finland|France|Germany|Hungary|Italy|Netherlands|Norway|Poland|Portugal|Romania|Russian Federation|Slovakia|Spain|Sweden|Ukraine|United Kingdom 1
Belgium 1
China|United States|Argentina|Australia|Brazil|Canada|Costa Rica|Czech Republic|Finland|France|Germany|Hong Kong|Mexico|Panama|Russian Federation|South Africa|Spain|Sweden|Thailand 1
Croatia 1
Cuba 1
Denmark 1
Denmark|Israel|Norway|Spain|United Kingdom 1
France 1
France|Austria|Belgium|Canada|Finland|Germany|Hungary|Mexico|Norway|South Africa|Sweden|Switzerland|United Kingdom 1
France|Switzerland 1
Germany 1
India 1
Japan|Taiwan 1
Jordan 1
Korea, Republic of 1
Philippines 1
Poland 1
Slovenia 1
Ukraine 1
United States|Argentina|Australia|Belgium|Bulgaria|Canada|Chile|Croatia|Czechia|Estonia|Finland|France|Hungary|Israel|Latvia|Lithuania|Mexico|New Zealand|Russian Federation|Serbia|Slovakia|Ukraine 1
United States|Argentina|Germany|Italy|Mexico 1
United States|Australia|Belgium|Canada|France|Germany|Iceland|Italy|Mexico|Netherlands|Puerto Rico|Sweden|Switzerland|United Kingdom 1
United States|Belgium|France|Germany|Italy 1
United States|Bulgaria|Chile|Croatia|Czech Republic|Estonia|Israel|Latvia|Lithuania|Mexico|Poland|Russian Federation|Serbia|Slovakia|Ukraine 1
United States|Bulgaria|Croatia|Czechia|Estonia|Israel|Latvia|Lithuania|Poland|Russian Federation|Serbia|Slovakia|Ukraine 1
United States|Canada 1
United States|Czechia|Hong Kong|Hungary|Korea, Republic of|Russian Federation|Serbia|Singapore|Slovakia|Spain|Taiwan|Turkey|Ukraine 1
United States|Dominican Republic|Puerto Rico 1
United States|Greece|Portugal 1

Sites per Study

Site_count Study_Count
1 70
2 8
3 5
4 3
5 3
6 1
7 1
8 1
9 2
10 1
11 1
13 1
17 1
18 1
21 1
22 1
25 1
27 1
28 1
35 1
38 1
39 1
55 1
67 1
70 1
71 1
74 1
121 1
133 1
146 1
168 1
182 1
217 1

Phase

Phase Study_Count
N/A 46
Phase 3 27
Phase 4 17
Phase 2 14
Phase 1 10
Phase 2/Phase 3 4

Number of Arms

Number_of_Arms Count_of_Studies
1 25
2 48
3 12
4 15
5 4
6 2
7 3
11 1
12 1
15 1
NA 6

Enrollment Metrics by Phase

Measure N.A Phase.1 Phase.2 Phase.2.Phase.3 Phase.3 Phase.4
Min. 14.0000 11.00 24.0 101.00 4.0000 12.0000
1st Qu. 45.0000 26.25 66.5 271.25 210.0000 30.0000
Median 117.0000 41.50 173.5 389.00 590.0000 75.0000
Mean 223.6522 165.30 243.0 484.25 586.7778 381.4118
3rd Qu. 284.5000 57.00 231.5 602.00 834.0000 252.0000
Max. 1611.0000 1307.00 1307.0 1058.00 1500.0000 2400.0000

Trial Group Type

group_type Group_Count
Experimental 165
Active Comparator 73
Placebo Comparator 48
No Intervention 11
Other 9
NA 6
Sham Comparator 2

Intervention Model

intervention_model Study_Count
Parallel Assignment 74
Single Group Assignment 29
Crossover Assignment 8
Factorial Assignment 5
Sequential Assignment 2

Primary Purpose

primary_purpose Study_Count
Treatment 78
Diagnostic 7
NA 7
Other 6
Supportive Care 6
Prevention 5
Basic Science 4
Health Services Research 4
Screening 1

Observational Studies

Studies by Country

Country Study_Count
United States 16
NA 7
China 2
France 2
Belgium 1
Brazil 1
Canada 1
Colombia 1
Croatia 1
Denmark 1
Germany 1
Italy 1
Japan 1
Kazakhstan 1
Slovakia 1
Taiwan 1
Thailand 1

Sites per Study

Site_count Study_Count
1 34
2 2
14 1
15 2
25 1

Enrollment Metrics

Measure Observational
Min 6.00
1st Qu 52.00
Median 106.50
Mean 2000.45
3rd Qu 612.00
Max 44587.00

Observation Model

observational_model Study_Count
Cohort 19
Case-Only 6
Other 5
Case-Control 3
NA 3
Case Control 2
Ecologic or Community 1
Family-Based 1

Time Perspective

time_perspective Study_Count
Prospective 16
Cross-Sectional 14
Retrospective 8
NA 2

Registries

Studies by Country

Country Study_Count
Italy 2
Turkey 1
United States 1

Sites per Study

Site_count Study_Count
1 3
2 1

Enrollment Metrics

Measure Registries
Min 60
1st Qu 69
Median 86
Mean 558
3rd Qu 575
Max 2000

Registry Model

observational_model Study_Count
Cohort 3
Case-Only 1

Time Perspective

time_perspective Study_Count
Prospective 3
Cross-Sectional 1

Follow-up

target_duration Study_Count
12 Months 2
1 Day 1
70 Months 1

Overview of Studies

Interventional Trials

#If less then 500 trials

nct_id brief_title link overall_status source primary_completion_date
NCT03355677 A Study Into Airways Disease Case Finding and Management https://ClinicalTrials.gov/show/NCT03355677 Completed University of Southampton 2019-12-31
NCT03333057 Perfluorohexyloctane (NOV03) for the Treatment of Signs and Symptoms of Dry Eye Disease (DED) https://ClinicalTrials.gov/show/NCT03333057 Completed Novaliq GmbH 2018-05-18
NCT03311048 Airway Inflammatory Profile Among Cleaning Workers From Different Workplaces https://ClinicalTrials.gov/show/NCT03311048 Completed University of Sao Paulo 2017-04-01
NCT03292809 CyclASol for the Treatment of Signs and Symptoms of Dry Eye Disease (DED) https://ClinicalTrials.gov/show/NCT03292809 Completed Novaliq GmbH 2018-05-22
NCT03287635 Clinical Efficacy of H.P. Acthar Gel 80 U/ml to Improve the Signs and Symptoms in Subjects With Dry Eye Disease https://ClinicalTrials.gov/show/NCT03287635 Recruiting Toyos Clinic 2020-05-31
NCT03273114 Cognitive Functional Therapy (CFT) Compared With Core Training Exercise and Manual Therapy (CORE-MT) in Patients With Chronic Low Back Pain https://ClinicalTrials.gov/show/NCT03273114 Recruiting Centro Universitário Augusto Motta 2020-01-15
NCT03221439 Cognitive Functional Therapy for Chronic Low Back Pain https://ClinicalTrials.gov/show/NCT03221439 Recruiting Centro Universitário Augusto Motta 2019-09-30
NCT03052049 Prostatic Artery Embolization (PAE) for Treatment of Signs and Symptoms of Benign Prostatic Hyperplasia (BPH) Using Bead Block Microspheres https://ClinicalTrials.gov/show/NCT03052049 Active, not recruiting Northwestern University 2020-03-01
NCT03003403 Balance: A Pragmatic Trial of a Digital Health Intervention to Prevent Weight Gain in Primary Care https://ClinicalTrials.gov/show/NCT03003403 Active, not recruiting Duke University 2020-12-31
NCT02931318 The Knowledge Levels and Attitudes of the People Living in NevÅŸehir on Organ Donation and Transplantation https://ClinicalTrials.gov/show/NCT02931318 Completed Nevsehir Public Hospital 2016-05-31
NCT02826408 Effect of Proton Pump Inhibitors on Palpitations https://ClinicalTrials.gov/show/NCT02826408 Completed Jordan Collaborating Cardiology Group 2018-03-31
NCT02821650 A Study to Test the Impact of an Improved Chulha on Respiratory Health of Women and Children in Indian Slums https://ClinicalTrials.gov/show/NCT02821650 Active, not recruiting Maastricht University 2020-08-31
NCT02706834 Safety, Tolerability and Pharmacokinetics of Escalating Single Doses of TAK-828 in Healthy Participants https://ClinicalTrials.gov/show/NCT02706834 Completed Takeda 2016-06-17
NCT02677090 Fiber Tolerability in Children Aged 3-7 Year https://ClinicalTrials.gov/show/NCT02677090 Completed Nestlé 2016-03-31
NCT02538601 Enhanced Smoking Cessation Intervention for Smokers Exposed to the World Trade Center (WTC) Disaster https://ClinicalTrials.gov/show/NCT02538601 Completed Stony Brook University 2014-11-30
NCT02532985 Gastrointestinal Tolerability Following Multiple Servings of a Novel Dietary Fiber https://ClinicalTrials.gov/show/NCT02532985 Completed Cargill 2015-03-31
NCT02530762 Acute Gastrointestinal Tolerability Following a Single Serving of a Novel Dietary Fiber https://ClinicalTrials.gov/show/NCT02530762 Completed Cargill 2014-12-31
NCT02519374 Fiber Tolerability in Children https://ClinicalTrials.gov/show/NCT02519374 Completed Nestlé 2015-07-31
NCT02457780 Stress Management Program for World Trade Center (WTC) Responders https://ClinicalTrials.gov/show/NCT02457780 Completed Stony Brook University 2016-12-31
NCT02334982 Safety, Tolerability and Pharmacokinetics of Escalating Single Doses of TAK-137 in Healthy Participants https://ClinicalTrials.gov/show/NCT02334982 Completed Takeda 2014-01-31
NCT02298517 Application Breathing Exercises With Load Inspiratory Postoperative Abdominal Surgery https://ClinicalTrials.gov/show/NCT02298517 Completed Universidade Metodista de Piracicaba 2014-10-31
NCT02253628 The Acute Effect of Coffee Consumption on Stomach, Self-reported Gastrointestinal Symptoms and Stress. https://ClinicalTrials.gov/show/NCT02253628 Completed Agricultural University of Athens 2014-06-30
NCT02244255 FLOMAX® Versus HYTRIN® in Patients With the Signs and Symptoms of Benign Prostatic Hyperplasia https://ClinicalTrials.gov/show/NCT02244255 Completed Boehringer Ingelheim 2000-06-30
NCT02244242 Study to Evaluate the Symptomatic Relief Effects of FLOMAX® in Patients With Signs and Symptoms of Benign Prostatic Hyperplasia https://ClinicalTrials.gov/show/NCT02244242 Completed Boehringer Ingelheim 1999-08-31
NCT02210689 A Multi-center, Double-blind, Randomized Study, Comparing Clindamycin Phosphate Vaginal Cream 2% (Watson Laboratories, Inc.) to Clindesse® (Ther-Rx™, Clindamyin Phosphate Vaginal Cream 2%) and Both Active Treatments to a Placebo Control in the Treatment of Bacterial Vaginosis in Non-pregnant Women https://ClinicalTrials.gov/show/NCT02210689 Completed Actavis Inc. 2014-10-31
NCT02180035 Treatment With Nutritional Eating Plan and Dietary Fibers in Adult Patients With HIV/AIDS https://ClinicalTrials.gov/show/NCT02180035 Completed Conselho Nacional de Desenvolvimento Científico e Tecnológico 2011-07-31
NCT02175628 Comparison of the Sensitivity and Specificity of Acoustic Angiography to the Sensitivity and Specificity of Conventional Ultrasound https://ClinicalTrials.gov/show/NCT02175628 Completed UNC Lineberger Comprehensive Cancer Center 2018-06-30
NCT02157675 Effects of a Polyherbal Supplement on the Signs and Symptoms of Delayed Onset Muscle Soreness https://ClinicalTrials.gov/show/NCT02157675 Completed NewChapter, Inc. 2014-06-30
NCT02153099 Safety, Tolerability and Pharmacokinetics of Escalating Single Doses of ENV8058 (TAK-058) in Healthy Participants https://ClinicalTrials.gov/show/NCT02153099 Completed Takeda 2014-11-30
NCT02141698 Safety, Tolerability, and Pharmacokinetics of TAK-438 in Healthy Western Male Subjects, Preliminary Food Effect Analysis, and an Ethnic Comparison With Japanese Subjects https://ClinicalTrials.gov/show/NCT02141698 Completed Takeda 2008-02-29
NCT02125253 Study to Compare the Therapeutic Equivalence of Mometasone Furoate Nasal Spray, 50 mcg With Nasonex Nasal Spray in the Relief of the Signs and Symptoms of Seasonal Allergic Rhinitis https://ClinicalTrials.gov/show/NCT02125253 Completed Amneal Pharmaceuticals, LLC 2014-03-31
NCT02123953 Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of TAK-438 in Healthy Male Participants https://ClinicalTrials.gov/show/NCT02123953 Completed Takeda 2009-03-31
NCT02109185 A Comparison of Mometasone Nasal Spray, Nasonex Nasal Spray, Nasonex Nasal Spray Suspension, & Placebo for Treatment of Seasonal Allergies for Safety, Efficacy, & Superiority in 1520 Male & Female Volunteers https://ClinicalTrials.gov/show/NCT02109185 Completed Mylan Pharmaceuticals 2013-10-31
NCT02099591 Phase I Pharmacokinetics and Safety Study of Naloxegol in Paediatric OIC Patients https://ClinicalTrials.gov/show/NCT02099591 Active, not recruiting Kyowa Kirin Pharmaceutical Development Ltd 2021-07-31
NCT02075320 Evaluation of the Lung Nodule Sensitivity of Stationary Chest Tomosynthesis in Patients With Known Lung Nodules https://ClinicalTrials.gov/show/NCT02075320 Completed UNC Lineberger Comprehensive Cancer Center 2016-08-09
NCT01279057 A Study Comparing Two Fluticasone Furoate Nasal Sprays in the Relief of the Signs and Symptoms of Seasonal Allergic Rhinitis https://ClinicalTrials.gov/show/NCT01279057 Completed Sandoz 2011-02-28
NCT01954199 The Effectiveness of Neurodynamic Techniques in Patients With Nerve-Related Leg Pain https://ClinicalTrials.gov/show/NCT01954199 Completed Federal University of Health Science of Porto Alegre 2016-04-30
NCT01872663 Influence of Different Physical Therapy Resources Application After Reduction Stomach Surgery https://ClinicalTrials.gov/show/NCT01872663 Completed Universidade Metodista de Piracicaba 2013-12-31
NCT01824511 Effects of Quitting Study A Test of Pre-clinical Findings https://ClinicalTrials.gov/show/NCT01824511 Completed University of Vermont 2015-09-30
NCT01796925 Targeted Hypoglossal Neurostimulation Study #2 https://ClinicalTrials.gov/show/NCT01796925 Completed LivaNova 2013-09-30
NCT01786681 Use of Positive Pressure in Morbidly Obese Patients Undergoing Reduction Stomach Surgery https://ClinicalTrials.gov/show/NCT01786681 Completed Universidade Metodista de Piracicaba 2011-12-31
NCT01586676 Effectiveness of Motivational Interviewing Supervision in Community Programs https://ClinicalTrials.gov/show/NCT01586676 Completed National Institute on Drug Abuse (NIDA) 2013-09-30
NCT01532180 Safety and Efficacy of a Hypoglossal Nerve Implant for the Treatment of Obstructive Sleep Apnea (OSA) https://ClinicalTrials.gov/show/NCT01532180 Completed LivaNova 2011-12-31
NCT01500122 Study Evaluating the Pharmacokinetic Profile of Novel Formulations of RHUDEX® https://ClinicalTrials.gov/show/NCT01500122 Completed MediGene 2012-03-31
NCT01435603 Intervening in Diabetes With Healthy Eating, Activity, and Linkages To Healthcare - The I-D-HEALTH Study https://ClinicalTrials.gov/show/NCT01435603 Completed Northwestern University 2016-09-30
NCT01371565 Compassionate Use of CORLUX® (Mifepristone) in the Treatment of Signs and Symptoms of Endogenous Cushing’s Syndrome https://ClinicalTrials.gov/show/NCT01371565 Completed Corcept Therapeutics 2012-06-30
NCT01369771 The Effects of Preservative-free Prostaglandin Eye Drops in Sign and Symptoms on the Eyes of Patients With Glaucoma https://ClinicalTrials.gov/show/NCT01369771 Completed FinnMedi Oy 2012-06-30
NCT01357538 Efficacy and Safety of Posiformin 2 % Eye Ointment in the Treatment of Blepharitis https://ClinicalTrials.gov/show/NCT01357538 Completed Ursapharm Arzneimittel GmbH 2009-07-31
NCT01340027 A Study to Evaluate the Efficacy, Safety and Tolerability of Mirabegron and Solifenacin Succinate Alone and in Combination for the Treatment of Overactive Bladder https://ClinicalTrials.gov/show/NCT01340027 Completed Astellas Pharma Inc 2012-06-28
NCT04301700 Effects of Progressive Muscle Relaxation and Mindfulness Meditation in Patients With Chronic Obstructive Pulmonary Disease https://ClinicalTrials.gov/show/NCT04301700 Active, not recruiting Hacettepe University 2020-03-20
NCT04292665 Effects of Classical Massage and Benson Relaxation Exercise on Symptom Status and Quality of Life in Heart Failure Patients https://ClinicalTrials.gov/show/NCT04292665 Active, not recruiting Hacettepe University 2020-05-30
NCT04289142 Cognitive Outcomes After Dexmedetomidine Sedation in Cardiac Surgery Patients https://ClinicalTrials.gov/show/NCT04289142 Recruiting Sunnybrook Health Sciences Centre 2026-03-11
NCT04169919 Modified Treatment for Epidemic Keratoconjunctivitis (EKC) https://ClinicalTrials.gov/show/NCT04169919 Completed Minia University 2018-10-31
NCT04093206 Compare Effects of EpiCor and Vitamin C to Vitamin C Alone on the Common Cold or Influenza in Healthy Children https://ClinicalTrials.gov/show/NCT04093206 Completed Cargill 2019-03-28
NCT04036292 Clinical Trial to Evaluate the Efficacy of OC-01 (Varenicline) Nasal Spray on Signs and Symptoms of Dry Eye Disease (The ONSET-2 Study) https://ClinicalTrials.gov/show/NCT04036292 Active, not recruiting Oyster Point Pharma, Inc. 2020-05-08
NCT04032249 Implications of Self-weighing During Weight Loss Treatment https://ClinicalTrials.gov/show/NCT04032249 Active, not recruiting Universidad de Córdoba 2018-12-15
NCT04015219 Management of Signs and Symptoms Associated With Dry Eye Disease https://ClinicalTrials.gov/show/NCT04015219 Recruiting Tissue Tech Inc. 2020-07-01
NCT03985579 Influence of Kinesiology Taping Application on Severity of Signs and Symptoms in Breast Engorgement. https://ClinicalTrials.gov/show/NCT03985579 Recruiting Żelazna Medical Centre, LLC 2020-09-01
NCT03953560 Symptom-related Screening for Early Detection of CTEPH. https://ClinicalTrials.gov/show/NCT03953560 Recruiting Hospitales Universitarios Virgen del Rocío 2019-12-31
NCT03920215 Clinical Trial to Evaluate the Long Term Follow up of the Efficacy of OC-01 Nasal Spray on Signs and Symptoms of Dry Eye Disease (The ONSET Study) https://ClinicalTrials.gov/show/NCT03920215 Completed Oyster Point Pharma, Inc. 2019-10-12
NCT03763500 Evaluation of the Added Value of an Internet-based Educational Program for Patients With Atrial Fibrillation. https://ClinicalTrials.gov/show/NCT03763500 Recruiting Linkoeping University 2020-06-30
NCT03713359 Clinical Trial for Measles - Rubella Combined Vaccine (MRVAC) Produced by POLYVAC (Phase III) https://ClinicalTrials.gov/show/NCT03713359 Completed Center for Research and Production of Vaccines and Biologicals, Vietnam 2016-07-31
NCT03660475 Effect of Topical Naltrexone Ophthalmic Solution on the Signs and Symptoms of Dry Eye in Diabetic Subjects https://ClinicalTrials.gov/show/NCT03660475 Completed Total Eye Care, PA 2018-11-01
NCT03636061 Clinical Trial to Evaluate the Efficacy of OC-01 Nasal Spray on Signs and Symptoms of Dry Eye Disease (The ONSET-1 Study) https://ClinicalTrials.gov/show/NCT03636061 Completed Oyster Point Pharma, Inc. 2018-09-26
NCT03633461 Clinical Trial to Evaluate the Efficacy of OC-02 Nasal Spray on Signs and Symptoms of Dry Eye Disease (The RAINIER Study) https://ClinicalTrials.gov/show/NCT03633461 Completed Oyster Point Pharma, Inc. 2018-09-20
NCT03595189 Safety, Tolerability and Pharmacokinetic Profile of an Infusion of Cilastatin in Healthy Volunteers. https://ClinicalTrials.gov/show/NCT03595189 Completed Spherium Biomed 2018-08-09
NCT03544268 Academic-Industrial Partnership for Translation of Acoustic Angiography https://ClinicalTrials.gov/show/NCT03544268 Active, not recruiting UNC Lineberger Comprehensive Cancer Center 2021-02-28
NCT03542383 Treatment of Memory Disorders in Gulf War Illness With High Definition Transcranial Direct Cortical Stimulation https://ClinicalTrials.gov/show/NCT03542383 Recruiting The University of Texas at Dallas 2020-09-29
NCT03452397 Clinical Trial to Evaluate the Efficacy of OC-02 Nasal Spray on Signs and Symptoms of Dry Eye Disease (The PEARL Study) https://ClinicalTrials.gov/show/NCT03452397 Completed Oyster Point Pharma, Inc. 2018-05-16
NCT01268735 The Effect of Ocular Lubricant Eyedrops on Lid Parallel Conjunctival Folds and Other Signs and Symptoms of Dry Eye https://ClinicalTrials.gov/show/NCT01268735 Completed University of Zagreb 2009-09-30
NCT01214811 Open Multi-centre Investigation to Evaluate Signs and Symptoms of Local Inflammation/Infection on Chronic Ulcers and Partial Thickness Burns When Using Mepilex Border Ag as an Anti-microbial Wound Dressing https://ClinicalTrials.gov/show/NCT01214811 Completed Molnlycke Health Care AB 2011-09-30
NCT01043913 Guarana (Paullinia Cupana) for Breast Cancer Chemotherapy-related Fatigue https://ClinicalTrials.gov/show/NCT01043913 Completed Faculdade de Medicina do ABC 2009-09-30
NCT01043367 Deprexil in Subjects With Signs and Symptoms of Depression https://ClinicalTrials.gov/show/NCT01043367 Completed Catalysis SL 2011-01-31
NCT01038427 A Study Comparing the Clinical Equivalence of Two Mometasone Nasal Sprays in the Relief of the Signs and Symptoms of Seasonal Allergic Rhinitis https://ClinicalTrials.gov/show/NCT01038427 Completed Sandoz 2010-02-28
NCT00938587 A Study Of PF-04171327 In The Treatment Of The Signs And Symptoms Of Rheumatoid Arthritis https://ClinicalTrials.gov/show/NCT00938587 Completed Pfizer 2010-07-31
NCT00934713 The Effect of Montelukast Treatment in Wheezy Infants https://ClinicalTrials.gov/show/NCT00934713 Completed University of Helsinki 2008-04-30
NCT00861757 Multinational Study to Evaluate Tadalafil in Asian Men With Signs and Symptoms of Benign Prostatic Hyperplasia https://ClinicalTrials.gov/show/NCT00861757 Completed Eli Lilly and Company 2010-06-30
NCT00848120 A Study to Assess the Effect of Tocilizumab on Signs and Symptoms in Patients With Rheumatoid Arthritis https://ClinicalTrials.gov/show/NCT00848120 Completed Hoffmann-La Roche 2010-02-13
NCT03244202 Evaluation of a Decision Aid for Incidental Genomic Findings https://ClinicalTrials.gov/show/NCT03244202 Completed St. Michael’s Hospital, Toronto 2018-04-02
NCT01087671 Ocular Signs and Symptoms in Glaucoma Patients Switched From Latanoprost to Preservative Free Tafluprost Eye Drops https://ClinicalTrials.gov/show/NCT01087671 Completed Santen Oy 2010-10-31
NCT00827242 Study to Treat Patients Who Have Signs and Symptoms of Benign Prostatic Hyperplasia (BPH) With Tadalafil Daily https://ClinicalTrials.gov/show/NCT00827242 Completed Eli Lilly and Company 2009-11-30
NCT00822328 Fermented Milk Drink on Human Intestinal Microflora https://ClinicalTrials.gov/show/NCT00822328 Completed Cheng Hsin Rehabilitation Medical Center 2009-03-31
NCT01634958 Dose Finding Study Depigoid Phleum: 4 Doses in Patients With Allergic Rhinitis/Rhinoconjunctivitis +-Asthma https://ClinicalTrials.gov/show/NCT01634958 Completed Leti Pharma GmbH 2013-04-30
NCT04260035 The Effects of a Long-lasting Infusion of Vasoactive Intestinal Peptide (VIP) in Episodic Migraine Patients https://ClinicalTrials.gov/show/NCT04260035 Recruiting Danish Headache Center 2020-06-30
NCT03451396 Effect of Lifitegrast on Dry Eye Disease Signs and Symptoms https://ClinicalTrials.gov/show/NCT03451396 Completed Lifelong Vision Foundation 2018-02-01
NCT03104894 The Effect of Meibomian Glands Massage on Signs and Symptoms of Dry Eye https://ClinicalTrials.gov/show/NCT03104894 Completed Barzilai Medical Center 2017-09-30
NCT00784108 Optimizing Photodynamic Therapy of Cutaneous Neoplastic Diseases Via Structured Illumination and Real-time Dosimetry. https://ClinicalTrials.gov/show/NCT00784108 Completed University of California, Irvine 2012-09-30
NCT00754572 A Study to Assess the Effect of Tocilizumab Plus Methotrexate on Safety and Signs and Symptoms in Patients With Moderate to Severe Active Rheumatoid Arthritis https://ClinicalTrials.gov/show/NCT00754572 Completed Hoffmann-La Roche 2012-10-31
NCT00723541 Breast Lesion Analysis for Tomosynthesis Mammography https://ClinicalTrials.gov/show/NCT00723541 Completed University of Michigan 2016-07-12
NCT00718133 The Effect of Air Pollution on Lung Health Among Children Living in Haifa Bay Region, Israel https://ClinicalTrials.gov/show/NCT00718133 Completed Carmel Medical Center 2009-08-31
NCT00717899 The Effect of Air Pollution on Lung Health Among School Children Living in Haifa Bay Region https://ClinicalTrials.gov/show/NCT00717899 Completed Carmel Medical Center 2009-08-31
NCT00652834 Small Bowel Capsule Endoscopy Findings in Patients Receiving Cellcept® https://ClinicalTrials.gov/show/NCT00652834 Completed University of California, Los Angeles 2011-03-31
NCT00652808 Double-Blind, Double Dummy, Randomized Comparison Study to Evaluate the Efficacy and Safety of Valdecoxib 10 mg Once Daily and Naproxen 500 mg Twice Daily in Treating the Signs and Symptoms of Osteoarthritis of the Knee https://ClinicalTrials.gov/show/NCT00652808 Completed Pfizer NA
NCT00650455 Efficacy and Safety of Valdecoxib and Naproxen in Treating the Signs and Symptoms of Rheumatoid Arthritis (RA) in a Severe Rheumatoid Arthritis Patients https://ClinicalTrials.gov/show/NCT00650455 Completed Pfizer 2005-01-31
NCT00648258 A Double-Blind, Double Dummy, Randomized Comparison Study Of The Efficacy And Safety Of Valdecoxib 10mg Once Daily And Naproxen 500mg Twice Daily In Treating The Signs And Symptoms Of Osteoarthritis Of The Knee Or Hip In Taiwan https://ClinicalTrials.gov/show/NCT00648258 Completed Pfizer NA
NCT00643279 Chronicle Offers Management to Patients With Advanced Signs and Symptoms of Heart Failure (COMPASS-HF) https://ClinicalTrials.gov/show/NCT00643279 Completed Medtronic Cardiac Rhythm and Heart Failure 2005-06-30
NCT00596791 Ocular Signs and Symptoms in Glaucoma Patients Switched From Latanoprost 0.005% to Preservative Free Tafluprost Eye Drops https://ClinicalTrials.gov/show/NCT00596791 Completed Santen Oy 2008-07-31
NCT00576485 Spherical Aberration and Contrast Sensitivity in IOLs https://ClinicalTrials.gov/show/NCT00576485 Completed Federal University of Minas Gerais NA
NCT00548834 Efficacy and Safety of CDP870 Versus Placebo in the Treatment of the Signs and Symptoms of Rheumatoid Arthritis https://ClinicalTrials.gov/show/NCT00548834 Completed UCB Pharma 2004-07-31
NCT00464737 The Use of Rotigotine for Treatment of Reducing Signs and Symptoms of Fibromyalgia in Adults. https://ClinicalTrials.gov/show/NCT00464737 Completed UCB Pharma 2008-11-30
NCT00799682 Exploratory Study Comparing Signs and Symptoms in Patients With Ocular Hypertension or Glaucoma Using Xalatan R® or Travatan Z® https://ClinicalTrials.gov/show/NCT00799682 Completed Ophthalmic Consultants of Long Island 2011-01-31
NCT00799552 Safety and Efficacy Study of RX-10045 on the Signs and Symptoms of Dry Eye https://ClinicalTrials.gov/show/NCT00799552 Completed Resolvyx Pharmaceuticals, Inc 2009-05-31
NCT00401830 Assessing Efficacy and Safety of Lacosamide Compared to Placebo in Reducing Signs and Symptoms of Fibromyalgia Syndrome. https://ClinicalTrials.gov/show/NCT00401830 Completed UCB Pharma 2008-02-29
NCT00391846 Evaluation of Heart Failure Treatment Guided by N-terminal Pro B-type Natriuretic Peptide (NTproBNP) vs Clinical Symptoms and Signs Alone https://ClinicalTrials.gov/show/NCT00391846 Completed AstraZeneca 2009-01-31
NCT00386009 Effects of Tadalafil Once a Day for 12 Weeks in Men With Signs and Symptoms of Benign Prostatic Hyperplasia https://ClinicalTrials.gov/show/NCT00386009 Completed Eli Lilly and Company 2008-05-31
NCT00384930 Study of Tadalafil Once-a Day for 12 Weeks in Men With Signs and Symptoms of Benign Prostatic Hyperplasia https://ClinicalTrials.gov/show/NCT00384930 Completed Eli Lilly and Company 2007-10-31
NCT00378989 The Effectiveness of Health Advice and Occupational Health Intervention on Work Ability https://ClinicalTrials.gov/show/NCT00378989 Completed Evalua International 2005-10-31
NCT00359905 Evaluation of the Efficacy and Safety of Silodosin in the Treatment of the Signs and Symptoms of BPH https://ClinicalTrials.gov/show/NCT00359905 Completed Recordati Industria Chimica e Farmaceutica S.p.A. 2007-05-31
NCT00331929 Respiratory Health Study of Children in Kiryat Tivon https://ClinicalTrials.gov/show/NCT00331929 Completed Carmel Medical Center 2007-09-30
NCT00311844 A Study of the Effects of Desloratadine on Conjunctival Allergen Challenge-induced Ocular Signs and Symptoms (Study P04209) https://ClinicalTrials.gov/show/NCT00311844 Completed Merck Sharp & Dohme Corp. 2005-05-28
NCT00251992 Nexium Dyspepsia/AST https://ClinicalTrials.gov/show/NCT00251992 Completed AstraZeneca 2005-01-31
NCT00251914 Nexium Dyspepsia/AST https://ClinicalTrials.gov/show/NCT00251914 Completed AstraZeneca 2005-01-31
NCT00175877 A Study of the Safety and Effectiveness of Lyophilized Certolizumab Pegol in the Treatment of Signs and Symptoms of Rheumatoid Arthritis and in Prevention of Joint Damage in Patients With Active Rheumatoid Arthritis https://ClinicalTrials.gov/show/NCT00175877 Completed UCB Pharma 2012-02-29
NCT00160641 A Study of the Safety and Effectiveness of Liquid Certolizumab Pegol in the Treatment of Signs and Symptoms of Rheumatoid Arthritis and in Prevention of Joint Damage in Patients With Active Rheumatoid Arthritis https://ClinicalTrials.gov/show/NCT00160641 Completed UCB Pharma 2012-02-29
NCT00160602 A Study of Liquid Certolizumab Pegol as Additional Medication to Methotrexate in the Treatment of Signs and Symptoms of Rheumatoid Arthritis and in Prevention of Joint Damage in Patients With Active Rheumatoid Arthritis https://ClinicalTrials.gov/show/NCT00160602 Completed UCB Pharma 2006-09-30
NCT00106574 A Study to Assess the Effect of Tocilizumab + DMARD Therapy on Signs and Symptoms in Patients With Moderate to Severe Active Rheumatoid Arthritis https://ClinicalTrials.gov/show/NCT00106574 Completed Hoffmann-La Roche 2007-12-31
NCT00106548 A Study to Assess the Effect of Tocilizumab + Methotrexate on Signs and Symptoms in Patients With Moderate to Severe Active Rheumatoid Arthritis https://ClinicalTrials.gov/show/NCT00106548 Completed Hoffmann-La Roche NA
NCT00106522 A Study to Assess the Effect of Tocilizumab + Methotrexate on Signs and Symptoms in Patients With Moderate to Severe Active Rheumatoid Arthritis Currently on Methotrexate Therapy https://ClinicalTrials.gov/show/NCT00106522 Completed Hoffmann-La Roche 2007-11-30

Observational Studiess

#If less then 500 studies

nct_id brief_title link overall_status source primary_completion_date
NCT03336177 Understanding Low Gynecological Cancer Delay and Help-seeking Behavior in Older Patients. https://ClinicalTrials.gov/show/NCT03336177 Completed Institut de Cancérologie de Lorraine 2018-03-12
NCT03250988 Prevalence of Comorbid Spasticity and Urinary Incontinence in Residents of a Long-Term Care Facility https://ClinicalTrials.gov/show/NCT03250988 Completed Vanderbilt University Medical Center 2018-08-01
NCT03211390 Using Telemedicine to Improve Spasticity Diagnosis Rates https://ClinicalTrials.gov/show/NCT03211390 Completed Vanderbilt University Medical Center 2018-08-01
NCT03209960 Validity and Inter-Rater Reliability of a Novel Bedside Referral Tool for Spasticity https://ClinicalTrials.gov/show/NCT03209960 Completed Vanderbilt University Medical Center 2018-08-01
NCT03161392 Correlation of Solitary Dilated Duct at Mammography With Ultrasonography and Anatomopathological Findings https://ClinicalTrials.gov/show/NCT03161392 Completed Faculdade de Medicina do ABC 2017-03-13
NCT03009188 Genetic Findings in a Chinese Family With Axenfeld-Rieger Syndrom https://ClinicalTrials.gov/show/NCT03009188 Completed Aier Eye Hospital, Changsha 2016-12-31
NCT02889536 Living With a Parastomal Bulge - a Phenomenological-hermeneutic Study of Patients Lived Experiences https://ClinicalTrials.gov/show/NCT02889536 Completed Rigshospitalet, Denmark 2016-10-31
NCT02769559 Reduction Mammaplasty and Improved Quality of Life https://ClinicalTrials.gov/show/NCT02769559 Completed University Hospital Bratislava 2014-12-31
NCT02607293 A Study to Explore Correlation Between Symptoms and Signs of Polycystic Ovarian Syndrome (PCOS) and Risk of Over-response to Ovarian Stimulation https://ClinicalTrials.gov/show/NCT02607293 Completed Merck KGaA, Darmstadt, Germany 2017-03-16
NCT02482779 Smartphone Application-Based Vital Sign Monitors https://ClinicalTrials.gov/show/NCT02482779 Completed University of Texas Southwestern Medical Center 2015-06-30
NCT01316224 Prevalence and Incidence of Articular Symptoms and Signs Related to Psoriatic Arthritis in Patients With Psoriasis Severe or Moderate With Adalimumab Treatment https://ClinicalTrials.gov/show/NCT01316224 Completed AbbVie 2014-04-30
NCT01316029 Safety/Effectiveness Study of a Single Session of Laying-on-of-hands in Various Settings in Japan https://ClinicalTrials.gov/show/NCT01316029 Completed MOA Health Science Foundation 2007-12-31
NCT02012127 Description of Sign-and-symptom Associations at Acromegaly Diagnosis. https://ClinicalTrials.gov/show/NCT02012127 Completed Ipsen 2014-06-30
NCT01715376 Effects of Integrated Treatment by Traditional Chinese and Western Medicine in Reducing Cardiovascular Events https://ClinicalTrials.gov/show/NCT01715376 Completed Changchun University of Chinese Medicine 2013-09-30
NCT01631461 Painful Breastfeeding and Bacterial or Yeast Infection https://ClinicalTrials.gov/show/NCT01631461 Completed Göteborg University 2009-12-31
NCT01483703 Noninvasive Optical Measurement of Critical Care Neonates https://ClinicalTrials.gov/show/NCT01483703 Completed University of California, Irvine 2012-05-31
NCT01483495 Assessing Cerebrovascular Reactivity Based on Cerebral Oximetry: a Pilot Study https://ClinicalTrials.gov/show/NCT01483495 Completed University of California, Irvine 2011-12-31
NCT01431482 Evaluation of the Composition of Human Milk and Health Outcomes in Children https://ClinicalTrials.gov/show/NCT01431482 Completed Mead Johnson Nutrition 2012-06-30
NCT01396798 Validation of Vital Signs and Symptoms for the Diagnosis of Serious Infections in Children in the Paediatric A&E. https://ClinicalTrials.gov/show/NCT01396798 Completed KU Leuven 2012-03-31
NCT01394198 Correlation of Somatic Dysfunction With Gastrointestinal Endoscopic Findings https://ClinicalTrials.gov/show/NCT01394198 Completed A.T. Still University of Health Sciences 2013-11-30
NCT04437680 Retrospective Chart Review Study of Patients Treated With Votiva Device https://ClinicalTrials.gov/show/NCT04437680 Active, not recruiting InMode MD Ltd. 2020-06-30
NCT04436549 Pathology, Venous Disease, and Clinical Correlations https://ClinicalTrials.gov/show/NCT04436549 Recruiting University of Catanzaro 2020-09-01
NCT04393558 Wearable Sensor to Monitor COVID-19 Like Signs and Symptoms https://ClinicalTrials.gov/show/NCT04393558 Recruiting Shirley Ryan AbilityLab 2022-12-31
NCT04260620 Delphinus SoftVueâ„¢ ROC Reader Study (DMT SV RRS3) https://ClinicalTrials.gov/show/NCT04260620 Enrolling by invitation Delphinus Medical Technologies, Inc. 2020-03-03
NCT04081961 Feasibility Study to Use Biosensing Devices to Monitor PA and Resp. Function in Smokers w and w/o Resp. Symptoms/COPD https://ClinicalTrials.gov/show/NCT04081961 Completed Kazakhstan Academy of Preventive Medicine 2019-10-10
NCT04022564 Incidence, and Survival Medical Expenditure of Patients With Multiple Sclerosis https://ClinicalTrials.gov/show/NCT04022564 Active, not recruiting China Medical University Hospital 2020-05-20
NCT03994809 International Study of Biofield Therapy https://ClinicalTrials.gov/show/NCT03994809 Completed MOA Health Science Foundation 2010-09-30
NCT03972605 Delphinus SoftVueâ„¢ ROC Reader Study https://ClinicalTrials.gov/show/NCT03972605 Completed Delphinus Medical Technologies, Inc. 2019-07-02
NCT03939000 Clinical Profile and Laboratory Finding of DFU From Tertiary Hospitals in Bali https://ClinicalTrials.gov/show/NCT03939000 Completed Udayana University 2018-12-31
NCT03736824 Correlation of Endoscopic Findings and Symptoms in Patients Undergoing the First Upper Gastrointestinal Endoscopy https://ClinicalTrials.gov/show/NCT03736824 Recruiting Shanghai Jiao Tong University School of Medicine 2018-11-30
NCT03608735 Prevalence of Functional Gastrointestinal Disorders (FGIDs), Related Signs and Symptoms in Infants/Toddlers in Thailand https://ClinicalTrials.gov/show/NCT03608735 Completed Danone Asia Pacific Holdings Pte, Ltd. 2019-01-15
NCT03540004 Evaluation of MolecuLight i:X as an Adjunctive Fluorescence Imaging Tool to Clinical Signs and Symptoms for the Identification of Bacteria-containing Wounds https://ClinicalTrials.gov/show/NCT03540004 Active, not recruiting MolecuLight Inc. 2019-04-09
NCT03471923 Non-Motor Features of Cervical Dystonia (CD) https://ClinicalTrials.gov/show/NCT03471923 Completed Vanderbilt University Medical Center 2019-12-02
NCT03435614 Signs and Symptoms of Opioid-associated Iatrogenic Withdrawal in Critically Ill Adults https://ClinicalTrials.gov/show/NCT03435614 Completed McGill University Health Centre/Research Institute of the McGill University Health Centre 2018-09-30
NCT00985075 A Pilot Study Evaluating the Signs and Symptoms of Seasonal Allergic Rhinoconjunctivitis Following Exposure in the Allergen BioCube https://ClinicalTrials.gov/show/NCT00985075 Completed ORA, Inc. 2009-06-30
NCT00984529 Evaluation of Clinical Signs and Symptoms of Chronic Heart Failure in Patients Treated With Candesartan Cilexetil in Croatia https://ClinicalTrials.gov/show/NCT00984529 Completed AstraZeneca 2010-02-28
NCT00955422 Screening and Evaluation of Patients With Signs and Symptoms of Alzheimer’s Disease https://ClinicalTrials.gov/show/NCT00955422 Completed National Institutes of Health Clinical Center (CC) NA
NCT00869479 Validation of a Questionnaire to Identify Signs and Symptoms of Nephrogenic Systemic Fibrosis https://ClinicalTrials.gov/show/NCT00869479 Completed Massachusetts General Hospital 2010-09-30
NCT01679821 Prevalence of Signs and Symptoms of TMD in Patients Wearing Double Complete Dentures, RPD and in Dentistry Students. https://ClinicalTrials.gov/show/NCT01679821 Completed Universidade Estadual do Oeste do Paraná 2011-03-31
NCT00230932 Help Veterans Experience Less Pain Study (HELP-Vets) https://ClinicalTrials.gov/show/NCT00230932 Completed VA Office of Research and Development 2007-06-30

Registries

#If less then 500 registries

nct_id brief_title link overall_status source primary_completion_date
NCT04152902 Quality of Life After Surgery for End-stage Achalasia https://ClinicalTrials.gov/show/NCT04152902 Completed University of Bologna 2018-07-31
NCT03898570 Distributed Registry https://ClinicalTrials.gov/show/NCT03898570 Recruiting Stanford University 2019-09-30
NCT03543709 Evaluation of Fibromyalgia With Disease Activity and Clinical Findings in Women With Behçet’s Disease https://ClinicalTrials.gov/show/NCT03543709 Completed Bursa Yüksek İhtisas Education and Research Hospital 2019-02-05
NCT03505801 Confirm Rx SMART Registry https://ClinicalTrials.gov/show/NCT03505801 Recruiting Abbott Medical Devices 2020-01-31